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Search Result

Search Results for " fgfr 1 "

43

Compounds

1747

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T39001 FGFR-IN-1
FGFR-IN-1 is a highly effective inhibitor targeting the Fibroblast Growth Factor Receptor (FGFR) group, comprising FGFR1, FGFR2, and FGFR3, with an impressive inhibitory concentration (IC 50) of less than 100 nM (US20130...
T37426 FIIN-1 FGFR irreversible inhibitor-1 FGFR
FIIN-1 (FGFR irreversible inhibitor-1) is an irreversible and selective FGFR inhibitor with Kd of 2.8, 6.9, 5.4, 120, 32 and 120 nM for FGFR1, FGFR2, FGFR3, FGFR4, Flt1, Flt14, respectively.FIIN-1 inhibited FGFR1, FGFR2,...
T5044 Futibatinib TAS120,FGFR-IN-1 FGFR
Futibatinib (FGFR-IN-1) is a novel, potent and highly selective FGFR inhibitor, used for antitumor treatment.
TQ0256 FGFR4-IN-1 FGFR
FGFR4-IN-1 is a potent FGFR4 inhibitor (IC50: 0.7 nM).
T11279 FGFR1/DDR2 inhibitor 1 Discoidin Domain Receptor (DDR) , FGFR , Others
FGFR1/DDR2 inhibitor 1 is an inhibitor of discoindin domain receptor 2 (DDR2) and fibroblast growth factor receptor 1 (FGFR1), with IC50 values of 31.1 nM, 108.4 nM and 3.2 nM for FGFR1, KG-1, and DDR2, respectively.
T5466 Tyrosine kinase-IN-1 VEGFR , FGFR , FLT , PDGFR
Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor（KDR, Flt-1, FGFR1 and PDGFRα with IC50s of 4nM, 20nM, 4nM, 2 nM ,respectively）
TQ0015 PRN1371 c-Fms , FGFR , CSF-1R
PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).
T3466 FIIN-3 EGFR , FGFR
FIIN-3 is an irreversible inhibitor of FGFR.
T6932 PD168393 Apoptosis , EGFR , FGFR , IGF-1R , PDGFR , PKC , Autophagy
PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.
T8976 PD-089828 EGFR , FGFR , PDGFR , Src
PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 µM, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 ...
T23127 PD-161570 PD 161570 EGFR , FGFR , PDGFR , Src
PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, a...
T39992 FGFR1 inhibitor-2 FGFR1 inhibitor-2
FGFR1 inhibitor-2 (with an IC50 of 4.55 μM in MDA-MB-231 cells) is a potent inhibitor of FGFR1. It is specifically useful for studying metastatic triple-negative breast cancer.
T6930 Pazopanib Hydrochloride GW786034,Pazopanib HCl,GW786034 HCl,Votrient HCl,Armala c-Fms , VEGFR , FGFR , PDGFR , c-Kit , Autophagy
Pazopanib Hydrochloride (Votrient HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, resp...
T6289 Dovitinib TKI258,CHIR-258 VEGFR , FGFR , FLT , PDGFR , c-Kit
Dovitinib (CHIR-258) (TKI258, CHIR258) is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit, IC50: 1/2 nM), also effective to class IV (FGFR1/3) and class V (VEGFR1-4) RTKs (IC50: 8-13 nM), less potent to E...
T6028 PF 477736 PF 00477736,PF-477736,PF-736,PF-00477736,PF477736 c-Fms , VEGFR , FGFR , FLT , c-RET , Chk , CDK , Src , Aurora Kinase
PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (CSF1R), Ret and Yes.
T1975 Infigratinib BGJ-398,NVP-BGJ398 Apoptosis , FGFR
Infigratinib (NVP-BGJ398) (BGJ398) is an orally bioavailable pan FGFR inhibitor (IC50: 0.9/1.4/1 nM for FGFR1/2/3), >40-fold selective for FGFR versus FGFR4 and VEGFR2.
T16781 Rogaratinib BAY1163877 FGFR
Rogaratinib (BAY1163877) is an aberrant inhibitor of fibroblast growth factor receptor (FGFR). Rogaratinib is as an orally available, selective and potent inhibitor of FGFR-1, -2 and -3 kinase activity.
T6036 Brivanib BMS-540215 EGFR , VEGFR , FGFR , Autophagy
Brivanib (BMS-540215) is an ATP-competitive inhibitor against VEGFR2 with IC50 of 25 nM, moderate potency against VEGFR-1 and FGFR-1, but >240-fold against PDGFR-β. Phase 3.
T16364 Infigratinib phosphate NVP-BGJ398 phosphate,BGJ-398 phosphate FGFR
Infigratinib phosphate (BGJ-398 phosphate) is an effective inhibitor of the FGFR family (IC50: 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively).
T5473 ASP5878 ASP-5878 FGFR
ASP5878 potently inhibited the tyrosine kinase activities of recombinant FGFR1, 2, 3, and 4 with IC50 values of 0.47, 0.60, 0.74, and 3.5 nmol/L.
T2041 PD153035 NSC 669364,SU-5271,ZM 252868,AG1517 EGFR
PD153035 (NSC-669364) hydrochloride is an effective and selective inhibitor of EGFR (Ki/IC50: 5.2/29 pM, in cell-free assays); little inhibitory against FGFR, PGDFR, InsR, CSF-1 and Src.
T61304 FGFR2-IN-1 FGFR
FGFR2-IN-1 is an FGFR inhibitor that inhibits FGFR1, FGFR2, and FGFR3 with IC50s of 460, 140, and 2200 nM, respectively.FGFR2-IN-1 can be used for the study of cancers associated with FGFR2.CAS 번호13460-73-81-1
T2496 (Z)-Semaxinib SU5416 VEGFR
(Z)-Semaxinib (SU5416) is a potent and selective VEGFR(Flk-1/KDR) inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR over PDGFRβ, no inhibition for FGFR, InsR, and EGFR. (Z)-Semaxinib is a quinolone derivative w...
T1761 PD153035 hydrochloride ZM 252868 HCl,AG 1517,Tyrphostin AG 1517,SU 5271,PD153035 HCl,ZM 252868 EGFR
PD153035 hydrochloride (ZM 252868) is a effective and selective inhibitor of EGFR (Ki: 5.2 pM, IC50: 29 pM); few influence against FGFR, PGDFR, InsR, CSF-1, and Src.
T60108 PDGFR Tyrosine Kinase Inhibitor III PDGF Receptor Tyrosine Kinase Inhibitor III PDGFR
PDGFR Tyrosine Kinase Inhibitor III (PDGF Receptor Tyrosine Kinase Inhibitor III) (PDGF Receptor Tyrosine Kinase Inhibitor III) is a multikinase inhibitor that inhibits PDGFR, EGFR, FGFR, PKA, and PKC, respectively. PDGF...
T4425 JK-P3 VEGFR
JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube format...
T2064 Semaxinib SU5416 VEGFR
Semaxinib (SU5416) is a potent and selective VEGFR2 inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR than PDGFRβ, lack of activity against InsR, EGFR, and FGFR. Semaxanib reversibly inhibits ATP binding to the...
T62653 FGFR-IN-2
FGFR-IN-2 (compound 1) is a potent inhibitor of FGFR, acting on FGFR1 (IC50: 7.3 nM), FGFR2 (IC50: 4.3 nM), FGFR3 (IC50: 7.6 nM) and FGFR4 (IC50: 11 nM).
T61660 FGFR-IN-3
FGFR-IN-3 (compound 6) is a highly potent and orally active modulator of FGFR (fibroblast growth factor receptor). It has the ability to penetrate the blood-brain barrier (BBB). Additionally, FGFR-IN-3 exhibits significa...
T61528 FGFR-IN-7
FGFR-IN-7 (compound 17) is an orally active, potent FGFR modulator with the ability to penetrate the blood-brain barrier. It exhibits neuroprotective properties, enhancing brain exposure and decreasing the likelihood of ...
T79856 Resigratinib KIN-3248 FGFR
Resigratinib (KIN-3248) is a FGFR tyrosine kinase inhibitor exhibiting antineoplastic activity [1].
T79020 ALK2-IN-5
ALK2-IN-5, a pyrazolopyrimidine compound, serves as an inhibitor of ALK2 and FGFR, targeting disorders linked with their activity, including cancer [1].
T79880 FGFR4-IN-16 FGFR
FGFR4-IN-16 (CY-15-2) is a covalent inhibitor targeting FGFR-4, utilized in cancer research [1].
T64107 FGFR3-IN-1
FGFR3-IN-1 (compound 1) is a fibroblast growth factor receptor (FGFR) inhibitor that inhibits FGFR1 (IC50: 40 nM), FGFR2 (IC50: 5.1 nM) and FGFR3 (IC50: 12 nM).
T79257 FGFR-IN-11 FGFR
FGFR-IN-11 (compound I-5) is an orally active, covalent inhibitor of FGFR, exhibiting IC50 values of 9.9 nM (FGFR1), 3.1 nM (FGFR2), 16 nM (FGFR3), and 1.8 nM (FGFR4). This compound demonstrates nanomolar potency in inhi...
T71944 FGF/PDGF/VEGF RTK Inhibitor
FGF/PDGF/VEGF RTK Inhibitor is a potent, reversible, atp-competitive inhibitor against pdgfrβ, fgfr-1, and vegfr-2 (ic50 = 20, 90, and 240 nm, respectively) and effectively suppresses vegf-stimulated proliferation of h...
T61666 SUN13837
SUN13837 is an orally active, potent modulator of the fibroblast growth factor receptor (FGFR) with the ability to penetrate the blood-brain barrier (BBB). It exhibits neuroprotective activity and holds promise for furth...
T82404 FGFR3-IN-7 FGFR
FGFR3-IN-7 is a potent, selective inhibitor of FGFR 3, demonstrating an IC50 value of less than 350 nM , and is utilized in cancer research [1].
T62652 CPL304110
CPL304110 is an orally active, selective and potent inhibitor of the fibroblast growth factor receptor FGFR (1-3), acting on FGFR1 (IC50: 0.75 nM), FGFR2 (IC50: 0.5 nM), FGFR3 (IC50: 3.05 nM).
T82405 FGFR3-IN-6 FGFR
FGFR3-IN-6 is a potent, selective inhibitor of FGFR 3, exhibiting an IC50 value of less than 350 nM , and is utilized in cancer research [1].
T63967 Multi-kinase-IN-2
Multi-kinase-IN-2 is an orally active inhibitor of angiokinases. multi-kinase-IN-2 significantly inhibits the activity of angiokinases such as VEGFR-1/2/3, PDGFRα/β, FGFR-1, LYN and c-KIT kinases. -IN-2 significantly att...
T68286 CE-245677 mesylate
CE-245677 is a selective, orally active Tie2 kinase inhibitor identified by Pfizer previously in development for the treatment of certain cancers. CE-245,677 is a potent reversible inhibitor of Tie2 and TrkA/B kinases w...
T79850 Irpagratinib ABSK011 FGFR
Irpagratinib (ABSK011) is an orally active fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor with specificity for FGFR4, exhibiting an IC50 of less than 10 nM. It effectively inhibits FGFR4 auto-phosphor...

Compounds

FGFR-IN-1
T39001
Synonym:
Target:
FIIN-1
T37426
Synonym: FGFR irreversible inhibitor-1
Target: FGFR
Futibatinib
T5044
Synonym: TAS120,FGFR-IN-1
Target: FGFR
FGFR4-IN-1
TQ0256
Synonym:
Target: FGFR
FGFR1/DDR2 inhibitor 1
T11279
Synonym:
Target: Discoidin Domain Receptor (DDR), FGFR, Others
Tyrosine kinase-IN-1
T5466
Synonym:
Target: VEGFR, FGFR, FLT, PDGFR
PRN1371
TQ0015
Synonym:
Target: c-Fms, FGFR, CSF-1R
FIIN-3
T3466
Synonym:
Target: EGFR, FGFR
PD168393
T6932
Synonym:
Target: Apoptosis, EGFR, FGFR, IGF-1R, PDGFR, PKC, Autophagy
PD-089828
T8976
Synonym:
Target: EGFR, FGFR, PDGFR, Src
PD-161570
T23127
Synonym: PD 161570
Target: EGFR, FGFR, PDGFR, Src
FGFR1 inhibitor-2
T39992
Synonym: FGFR1 inhibitor-2
Target:
Pazopanib Hydrochloride
T6930
Synonym: GW786034,Pazopanib HCl,GW786034 HCl,Votrient HCl,Armala
Target: c-Fms, VEGFR, FGFR, PDGFR, c-Kit, Autophagy
Dovitinib
T6289
Synonym: TKI258,CHIR-258
Target: VEGFR, FGFR, FLT, PDGFR, c-Kit
PF 477736
T6028
Synonym: PF 00477736,PF-477736,PF-736,PF-00477736,PF477736
Target: c-Fms, VEGFR, FGFR, FLT, c-RET, Chk, CDK, Src, Aurora Kinase
Infigratinib
T1975
Synonym: BGJ-398,NVP-BGJ398
Target: Apoptosis, FGFR
Rogaratinib
T16781
Synonym: BAY1163877
Target: FGFR
Brivanib
T6036
Synonym: BMS-540215
Target: EGFR, VEGFR, FGFR, Autophagy
Infigratinib phosphate
T16364
Synonym: NVP-BGJ398 phosphate,BGJ-398 phosphate
Target: FGFR
ASP5878
T5473
Synonym: ASP-5878
Target: FGFR
PD153035
T2041
Synonym: NSC 669364,SU-5271,ZM 252868,AG1517
Target: EGFR
FGFR2-IN-1
T61304
Synonym:
Target: FGFR
(Z)-Semaxinib
T2496
Synonym: SU5416
Target: VEGFR
PD153035 hydrochloride
T1761
Synonym: ZM 252868 HCl,AG 1517,Tyrphostin AG 1517,SU 5271,PD153035 HCl,ZM 252868
Target: EGFR
PDGFR Tyrosine Kinase Inhibitor III
T60108
Synonym: PDGF Receptor Tyrosine Kinase Inhibitor III
Target: PDGFR
JK-P3
T4425
Synonym:
Target: VEGFR
Semaxinib
T2064
Synonym: SU5416
Target: VEGFR
FGFR-IN-2
T62653
Synonym:
Target:
FGFR-IN-3
T61660
Synonym:
Target:
FGFR-IN-7
T61528
Synonym:
Target:
Resigratinib
T79856
Synonym: KIN-3248
Target: FGFR
ALK2-IN-5
T79020
Synonym:
Target:
FGFR4-IN-16
T79880
Synonym:
Target: FGFR
FGFR3-IN-1
T64107
Synonym:
Target:
FGFR-IN-11
T79257
Synonym:
Target: FGFR
FGF/PDGF/VEGF RTK Inhibitor
T71944
Synonym:
Target:
SUN13837
T61666
Synonym:
Target:
FGFR3-IN-7
T82404
Synonym:
Target: FGFR
CPL304110
T62652
Synonym:
Target:
FGFR3-IN-6
T82405
Synonym:
Target: FGFR
Multi-kinase-IN-2
T63967
Synonym:
Target:
CE-245677 mesylate
T68286
Synonym:
Target:
Irpagratinib
T79850
Synonym: ABSK011
Target: FGFR

Recombinant Proteins

Species：
Human (1435)
Mouse (228)
Cynomolgus (25)
Rat (25)
Chinese hamster (4)
RSV (4)
Phleum pratense (3)
Human (2)
Human,Cynomolgus,Rhesus (2)
Human,Cynomolgus,Rhesus macaque (2)
Expression System：
HEK293 (1321)
E. coli (205)
Baculovirus-Insect Cells (186)
CHO (14)
Human Cells (11)
Yeast (10)
Tag：
His (701)
hFc (229)
C-His-Avi (183)
Tag Free (106)
C-His (95)
His,GST (74)
C-hFc (54)
mFc (40)
His,AVI (39)
GST (38)
Cat No. Product Name Species Expression System
TMPY-06034 FGFR1 Protein, Human, Recombinant (beta (IIIb), His) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-06036 FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-01011 FGFR1 Protein, Human, Recombinant (His) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPK-00394 FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in num...
TMPK-00392 FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi) Human HEK293
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in num...
TMPJ-01224 FGFRL1 Protein, Human, Recombinant (His) Human Human Cells
Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consists of a 354 amino acid extracellular domain (ECD) with 3 I...
TMPY-01781 FGFR1 Protein, Mouse, Recombinant (His) Mouse HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-01782 FGFR1 Protein, Mouse, Recombinant (hFc) Mouse HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-05761 FGFR1 Protein, Human, Recombinant (His), Biotinylated Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-01360 FGFRL1 Protein, Mouse, Recombinant (His) Mouse HEK293
Fibroblast growth factor receptor-like 1 (FGFRL1) also known as Fibroblast growth factor receptor 5 (FGFR5), is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserv...
TMPY-04371 FGFR1 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-05777 FGFR1 Protein, Human, Recombinant (hFc) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-06033 FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPY-06035 FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc) Human HEK293
FGFR1, also known as CD331, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another i...
TMPJ-00391 FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) Human Human Cells
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPJ-00390 FGFR2IIIb Protein, Human, Recombinant (hFc) Human Human Cells
FGFR2, also known as CD332, belongs to the fibroblast growth factor receptor subfamily where amino acid sequence is highly conserved between members and throughout evolution. FGFR2 acts as cell-surface receptor for fibro...
TMPJ-00715 FGF-19 Protein, Human, Recombinant (His) Human E. coli
Fibroblast growth factor 19 (FGF19) is a secreted protein which belongs to the FGFs family. FGF19 is expressed in fetal brain, cartilage, retina, and adult gall bladder. FGFs modulate cellular activity via at least 5 dis...
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus-Insect Cells
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) Human HEK293
Integrin alpha-5, also known as ITGA5, is a single-pass type I membrane protein which belongs to the integrin alpha chain family. ITGA5 contains 7 FG-GAP repeats. Alpha chain 5 undergoes post-translational cleavage in th...
TMPY-02501 CD3D & CD3E Heterodimer Protein, Human, Recombinant Human HEK293
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 cells.
TMPY-03745 CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) Human HEK293
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 with Flag and His tag. The predicted molecular weight is 31.05 kDa. Accession number: P04234-1&P07766-1
TMPY-02794 TLR2 Protein, Human, Recombinant (aa 1-587, His) Human Baculovirus-Insect Cells
TLR2, also known as CD282, is a member of the Toll-like receptor (TLR) family. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They play a fundamental role in pathoge...
TMPY-03947 CD48 Protein, Human, Recombinant (hFc) Human HEK293
Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD4...
TMPY-03481 IL-1R2 Protein, Human, Recombinant Human HEK293
Interleukin 1 receptor, type II (IL1R2) also known as CD121b (Cluster of Differentiation 121b) is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein binds interleukin alpha (IL1A), interl...
TMPK-00114 C-Reactive Protein /CRP Protein, Human, Recombinant (His) Human HEK293
C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate ...
TMPY-00740 SDF-1 Protein, Human, Recombinant (hFc) Human HEK293
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms f...
TMPY-04384 Src Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Proto-oncogene tyrosine-protein kinase SRC is a hydrophobic protein belonging to the SRC family kinase including nine members that is a family of non-receptor tyrosine kinases. SRC protein may exist in different forms: C...
TMPK-01151 MXRA8 Protein, Human, Recombinant (His) Human HEK293
Mxra8 is a recently described receptor for multiple alphaviruses, including Chikungunya (CHIKV), Mayaro (MAYV), Ross River (RRV), and O'nyong nyong (ONNV) viruses.
TMPK-01074 CD163 Protein, Human, Recombinant (His & Avi) Human HEK293
The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in ...
TMPK-00383 ACE2/ACEH Protein, Human, Recombinant (His & Avi) Human HEK293
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angio...
TMPY-02525 RGMA Protein, Human, Recombinant (His) Human HEK293
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein th...
TMPY-04753 IRE1 Protein, Human, Recombinant (aa 465-977) Human Baculovirus-Insect Cells
Endoplasmic reticulum stress and hypoxia are necessary components of malignant tumors growth and suppression of ERN1 (from endoplasmic reticulum to nuclei-1) signalling pathway, which is linked to the apoptosis and cell ...
TMPY-04413 IRE1 Protein, Human, Recombinant (aa 465-977, His & GST) Human Baculovirus-Insect Cells
Endoplasmic reticulum stress and hypoxia are necessary components of malignant tumors growth and suppression of ERN1 (from endoplasmic reticulum to nuclei-1) signalling pathway, which is linked to the apoptosis and cell ...
TMPK-01393 Tenascin Protein, Mouse, Recombinant (His) Mouse HEK293
Tenascin-C (TNC) is a hexameric, multimodular extracellular matrix protein with several molecular forms that are created through alternative splicing and protein modifications. It is highly conserved amongst vertebrates,...
TMPK-00305 TGFBR1 Protein, Human, Recombinant (mFc & Avi) Human HEK293
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the sup...
TMPY-01460 ABHD4 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain...
TMPY-00978 Progranulin Protein, Human, Recombinant (His) Human HEK293
Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The precursor protein, progranulin, ...
TMPY-02227 IL-1 beta/IL-1F2 Protein, Rat, Recombinant (mature form) Rat E. coli
Interleukin-1 beta (IL1 beta or IL1B) also known as catabolin, is a member of the interleukin 1 cytokine family. IL1 is a pleiotropic cytokine. It is involved in the inflammatory response, cell growth, and tissue repair ...
TMPY-05526 Siglec-15 Protein, Human, Recombinant (His) Human HEK293
Siglec-15 Protein, Human, Recombinant (His) is expressed in HEK293 cells.
TMPY-01963 IL-21 Protein, Human, Recombinant Human E. coli
IL21 belongs to the IL-15/IL-21 family. It is a cytokine with immunoregulatory activity. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellul...
TMPY-05781 LILRA6 Protein, Human, Recombinant (His) Human HEK293
LILRA6 Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 47.78 kDa. Accession number: Q6PI73-1
TMPY-06077 LILRA1/LIR-6/CD85i Protein, Human, Recombinant (hFc) Human HEK293
LILRA1/LIR-6/CD85i Protein, Human, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 75.3 kDa. Accession number: O75019-1
TMPY-05364 CD8 alpha Protein, Human, Recombinant (hFc) Human HEK293
T-cell surface glycoprotein CD8 alpha chain, also known as CD8a, is a single-pass type I membrane protein. The CD8 glycoprotein is expressed by thymocytes, mature T cells and natural killer (NK) cells and has been imp...
TMPY-04799 IFNAR2 Protein, Human, Recombinant (His), Biotinylated Human HEK293
Interferon-alpha/beta receptor beta chain (IFNAR2) is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulate Janus protei...
TMPY-04970 TIGIT Protein, Human, Recombinant (hFc) Human HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a tr...
TMPY-04826 LILRB5/CD85c Protein, Human, Recombinant (His) Human HEK293
A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) le...
TMPY-05435 ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc) Human HEK293
The angiopoietin (ANGPT)-TIE2/TEK signaling pathway is essential for blood and lymphatic vascular homeostasis. ANGPT1 is a potent TIE2 activator, whereas ANGPT2 functions as a context-dependent agonist/antagonist. In dis...
TMPY-05208 PD-L1 Protein, Human, Recombinant Human HEK293
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
TMPY-05319 BCMA/TNFRSF17 Protein, Human, Recombinant (His) Human HEK293
Tumor necrosis factor receptor superfamily, member 17 (TNFRSF17), also known as B cell maturation antigen (BCMA) or CD269 antigen, is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in...
TMPY-04949 PD-L1 Protein, Human, Recombinant (His), Biotinylated Human HEK293
Programmed death-1 ligand-1 (PD-L1, CD274, B7-H1) has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune res...
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FGFR1 Protein, Human, Recombinant (beta (IIIb), His)
TMPY-06034
Species: Human
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
TMPY-06036
Species: Human
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (His)
TMPY-01011
Species: Human
Expression System: HEK293
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00394
Species: Human
Expression System: HEK293
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
TMPK-00392
Species: Human
Expression System: HEK293
FGFRL1 Protein, Human, Recombinant (His)
TMPJ-01224
Species: Human
Expression System: Human Cells
FGFR1 Protein, Mouse, Recombinant (His)
TMPY-01781
Species: Mouse
Expression System: HEK293
FGFR1 Protein, Mouse, Recombinant (hFc)
TMPY-01782
Species: Mouse
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (His), Biotinylated
TMPY-05761
Species: Human
Expression System: HEK293
FGFRL1 Protein, Mouse, Recombinant (His)
TMPY-01360
Species: Mouse
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (His & GST)
TMPY-04371
Species: Human
Expression System: Baculovirus-Insect Cells
FGFR1 Protein, Human, Recombinant (hFc)
TMPY-05777
Species: Human
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (beta (IIIb), hFc)
TMPY-06033
Species: Human
Expression System: HEK293
FGFR1 Protein, Human, Recombinant (alpha (IIIb), hFc)
TMPY-06035
Species: Human
Expression System: HEK293
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
TMPJ-00391
Species: Human
Expression System: Human Cells
FGFR2IIIb Protein, Human, Recombinant (hFc)
TMPJ-00390
Species: Human
Expression System: Human Cells
FGF-19 Protein, Human, Recombinant (His)
TMPJ-00715
Species: Human
Expression System: E. coli
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
TMPY-04451
Species: Human
Expression System: Baculovirus-Insect Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
TMPY-03878
Species: Human
Expression System: HEK293
CD3D & CD3E Heterodimer Protein, Human, Recombinant
TMPY-02501
Species: Human
Expression System: HEK293
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
TMPY-03745
Species: Human
Expression System: HEK293
TLR2 Protein, Human, Recombinant (aa 1-587, His)
TMPY-02794
Species: Human
Expression System: Baculovirus-Insect Cells
CD48 Protein, Human, Recombinant (hFc)
TMPY-03947
Species: Human
Expression System: HEK293
IL-1R2 Protein, Human, Recombinant
TMPY-03481
Species: Human
Expression System: HEK293
C-Reactive Protein /CRP Protein, Human, Recombinant (His)
TMPK-00114
Species: Human
Expression System: HEK293
SDF-1 Protein, Human, Recombinant (hFc)
TMPY-00740
Species: Human
Expression System: HEK293
Src Protein, Human, Recombinant (His & GST)
TMPY-04384
Species: Human
Expression System: Baculovirus-Insect Cells
MXRA8 Protein, Human, Recombinant (His)
TMPK-01151
Species: Human
Expression System: HEK293
CD163 Protein, Human, Recombinant (His & Avi)
TMPK-01074
Species: Human
Expression System: HEK293
ACE2/ACEH Protein, Human, Recombinant (His & Avi)
TMPK-00383
Species: Human
Expression System: HEK293
RGMA Protein, Human, Recombinant (His)
TMPY-02525
Species: Human
Expression System: HEK293
IRE1 Protein, Human, Recombinant (aa 465-977)
TMPY-04753
Species: Human
Expression System: Baculovirus-Insect Cells
IRE1 Protein, Human, Recombinant (aa 465-977, His & GST)
TMPY-04413
Species: Human
Expression System: Baculovirus-Insect Cells
Tenascin Protein, Mouse, Recombinant (His)
TMPK-01393
Species: Mouse
Expression System: HEK293
TGFBR1 Protein, Human, Recombinant (mFc & Avi)
TMPK-00305
Species: Human
Expression System: HEK293
ABHD4 Protein, Human, Recombinant (His)
TMPY-01460
Species: Human
Expression System: Baculovirus-Insect Cells
Progranulin Protein, Human, Recombinant (His)
TMPY-00978
Species: Human
Expression System: HEK293
IL-1 beta/IL-1F2 Protein, Rat, Recombinant (mature form)
TMPY-02227
Species: Rat
Expression System: E. coli
Siglec-15 Protein, Human, Recombinant (His)
TMPY-05526
Species: Human
Expression System: HEK293
IL-21 Protein, Human, Recombinant
TMPY-01963
Species: Human
Expression System: E. coli
LILRA6 Protein, Human, Recombinant (His)
TMPY-05781
Species: Human
Expression System: HEK293
LILRA1/LIR-6/CD85i Protein, Human, Recombinant (hFc)
TMPY-06077
Species: Human
Expression System: HEK293
CD8 alpha Protein, Human, Recombinant (hFc)
TMPY-05364
Species: Human
Expression System: HEK293
IFNAR2 Protein, Human, Recombinant (His), Biotinylated
TMPY-04799
Species: Human
Expression System: HEK293
TIGIT Protein, Human, Recombinant (hFc)
TMPY-04970
Species: Human
Expression System: HEK293
LILRB5/CD85c Protein, Human, Recombinant (His)
TMPY-04826
Species: Human
Expression System: HEK293
ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)
TMPY-05435
Species: Human
Expression System: HEK293
PD-L1 Protein, Human, Recombinant
TMPY-05208
Species: Human
Expression System: HEK293
BCMA/TNFRSF17 Protein, Human, Recombinant (His)
TMPY-05319
Species: Human
Expression System: HEK293
PD-L1 Protein, Human, Recombinant (His), Biotinylated
TMPY-04949
Species: Human
Expression System: HEK293
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